{"id":1166,"date":"2026-03-30T23:02:41","date_gmt":"2026-03-30T23:02:41","guid":{"rendered":"https:\/\/techtonicwebdesign.com\/works\/ansarylabs\/?post_type=medical-newsletter&#038;p=1166"},"modified":"2026-03-30T23:02:41","modified_gmt":"2026-03-30T23:02:41","slug":"sperm-dna-fragmentation-by-flow-cytometry","status":"publish","type":"medical-newsletter","link":"https:\/\/techtonicwebdesign.com\/works\/ansarylabs\/medical-newsletter\/sperm-dna-fragmentation-by-flow-cytometry\/","title":{"rendered":"Sperm DNA Fragmentation by Flow Cytometry"},"content":{"rendered":"<div class=\"container\">\n<div class=\"postbox pr-20 pt-50 pb-50\">\n<div class=\"row align-items-center justify-content-center\">\n<div class=\"col-lg-8 \">\n<article class=\"postbox__item format-image mb-60 transition-3\">\n<div class=\"postbox__content\">\n<div class=\"postbox__text mb-40\">\n<p>Male infertility is the commonest cause of infertility. It contributes to nearly 50% of the 15% of couples of reproductive age. (1) Unexplained infertility is a very unsatisfactory diagnosis for couple suffering from<br \/>\ninfertility. Some studies found that 80% of couples diagnosed with idiopathic infertility have sperm DNA damage (&gt;20% damage). This suggests that sperm DNA damage is the cause of infertility in a substantial number of men (2).<br \/>\nOffering this cases IVF or in some cases (IUI) without DNA testing can lead to treatments with very low chances of success.<br \/>\nFurther compelling reasons for testing sperm DNA come from its strong associations with miscarriage (3)<br \/>\nSperm fragmentation test may guide couples with low damage to intrauterine<br \/>\ninsemination (IUI) or in vitro fertilization (IVF) and guide those couples with high DNAdamage to ICSI(1)<br \/>\nSperm fragmentation test will help Couples to avoid the loss of valuable biological time, the cost of failed cycles and the headache ofrepeatedly unsuccessful cycles ofIVF treatment.<br \/>\nUnexplained infertility couples will get a diagnosis and thus directs to the best treatment<br \/>\nfor them. Clinics will have improved IVF success rates, a scientific rationale for using<br \/>\nICSI.<br \/>\n1.https:\/\/ac.els-cdn.com\/S1110569013000137\/1-s2.0-S1110569013000137-main.pdf?_tid=c325901b-b84e-4dc7-<br \/>\nb678-34e93bc5ab37&amp;acdnat=1550425023_52d2ce34218dd13b5c3e3d4c6299dc07<br \/>\n2.SimonLI,ProutskiM,StevensonD,JenningsJ,McManusD,LuttonSEM.LewisSpermDNAdamagehasnegative<br \/>\nassociationwith live birth rates afterIVF.ReprodBiomedOnline 2013;26:68\u201378.<br \/>\n3. Robinson L, GallosID,Conner SJ,RajkhowaM,MillerD, Lewis S,Kirkman-Brown J,Coomarasamy A.Theeffect of<br \/>\nspermDNAfragmentationonmiscarriagerates:asystematic reviewandmeta-analysis.HumReprod2012;27(10):2908\u201317<\/p>\n<\/div>\n<\/div>\n<\/article>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"body-overlay\"><\/div>\n<div class=\"brand-area pt-30 pb-30\">\n<div class=\"container\">\n<div class=\"row\">\n<div class=\"col-lg-12\">\n<div class=\"tp-section text-center\"><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"featured_media":1167,"parent":0,"template":"","meta":{"_acf_changed":false},"class_list":["post-1166","medical-newsletter","type-medical-newsletter","status-publish","has-post-thumbnail","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/techtonicwebdesign.com\/works\/ansarylabs\/wp-json\/wp\/v2\/medical-newsletter\/1166","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/techtonicwebdesign.com\/works\/ansarylabs\/wp-json\/wp\/v2\/medical-newsletter"}],"about":[{"href":"https:\/\/techtonicwebdesign.com\/works\/ansarylabs\/wp-json\/wp\/v2\/types\/medical-newsletter"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/techtonicwebdesign.com\/works\/ansarylabs\/wp-json\/wp\/v2\/media\/1167"}],"wp:attachment":[{"href":"https:\/\/techtonicwebdesign.com\/works\/ansarylabs\/wp-json\/wp\/v2\/media?parent=1166"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}